5-HT2 receptor

5-HT2 receptor

5 -Hydroxytryptamine (5 -HT; serotonin) has been implicated in the pathophysiology of migraine, and several drugs with potent 5 -HT2 receptor blocking activity.
Stimulation of 5 - HT2 receptors in mammals by agonists causes detrimental neurological, psychological, and circulatory effects. antagonists block the.
The serotonin receptors, also known as receptors or 5-HT receptors, are a .. "Contribution of 5 - HT2 receptor subtypes to sleep- wakefulness and respiratory control, and functional adaptations in knock-out mice lacking. For cocaine and other stimulant use disorders, however, the quest to 5-HT2 receptor pharmacotherapeutics is challenged because we lack effective medications to serve as reference compounds. Increases in the SERT after chronic cocaine have been reported in cells Kittler et al. International Union of Basic and Jude Finestera Pharmacology. What links here Related changes Upload file Special pages Permanent link Page cool math 5 nights at freddys game Wikidata item Cite this page. Moreover, activation of the dorsolateral PFC has also been observed in response to cocaine Kufahl et al. Conclusion Although cocaine abuse is a significant public health problem, 5-HT2 receptor effective pharmacotherapeutics are available to treat this disorder.
General Principles of Pharmacology - 01 - Drug receptors and binding

5-HT2 receptor - free

The use of medications in addiction therapy is a concept that is gaining acceptance, but one which is counter to the normative belief in the treatment field that it is inappropriate to treat drug addiction with a medication i. Medication effects on self-administration may vary as a function of multiple contributing variables, including the drug dose, the schedule of reinforcement, and the duration of daily sessions employed to establish stable self-administration. Incubation of cocaine craving after withdrawal. The development of effective approaches to treatment of cocaine addiction relies on well designed clinical research in drug-using subjects as well as preclinical research in which rigorous experimental control and specific behavioral and pharmacological manipulations can be undertaken to model and control the progression of drug exposure across time. International Union of Basic and Clinical Pharmacology.